{"id":2234,"date":"2024-05-19T07:38:47","date_gmt":"2024-05-19T05:38:47","guid":{"rendered":"https:\/\/kleefstrasyndrome.com\/?p=2234"},"modified":"2026-08-20T16:40:40","modified_gmt":"2026-08-20T14:40:40","slug":"kleefstra-growth-metabolism-2024","status":"publish","type":"post","link":"https:\/\/kleefstrasyndrome.com\/el\/kleefstra-growth-metabolism-2024\/","title":{"rendered":"\u0392\u03ac\u03c1\u03bf\u03c2, \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c3\u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Kleefstra: \u039d\u03ad\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 62 \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Kleefstra \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c9\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae. \u0397 \u03c5\u03c0\u03bf\u03c4\u03bf\u03bd\u03af\u03b1, \u03b7 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7, \u03bf\u03b9 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03bd\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c0\u03b7\u03c1\u03af\u03b1 \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c4\u03bf \u03b5\u03c0\u03af\u03ba\u03b5\u03bd\u03c4\u03c1\u03bf \u03c4\u03cc\u03c3\u03bf \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2. \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03cc\u03c3\u03bf \u03bc\u03b5\u03b3\u03b1\u03bb\u03ce\u03bd\u03b5\u03b9 \u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03ba\u03ad\u03bd\u03c4\u03c1\u03b1, \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf\u03bb\u03bf\u03ad\u03bd\u03b1 \u03c0\u03b9\u03bf \u03c3\u03b1\u03c6\u03ad\u03c2 \u03cc\u03c4\u03b9 \u03c4\u03bf Kleefstra \u03b4\u03b5\u03bd \u03b1\u03c6\u03bf\u03c1\u03ac \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039c\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd <strong>Arianne Bouman, Joyce Geelen, Joost Kummeling, Tjitske Kleefstra \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03c4\u03ce\u03bd<\/strong> \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b5 \u03b3\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03bc\u03b5 \u03c4\u03cc\u03c3\u03bf \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c4\u03c1\u03cc\u03c0\u03bf \u03c4\u03b7\u03bd <strong>\u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7, \u03c4\u03b7 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb<\/strong> \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03c9\u03bd \u03bc\u03b5 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Kleefstra. \u0397 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf <em>American Journal of Medical Genetics Part A<\/em>, \u03bc\u03b5 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ce\u03c4\u03b7 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 29 \u0394\u03b5\u03ba\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2023 \u03ba\u03b1\u03b9 \u03ad\u03bd\u03c4\u03b1\u03be\u03b7 \u03c3\u03c4\u03bf \u03c4\u03b5\u03cd\u03c7\u03bf\u03c2 \u039c\u03b1\u0390\u03bf\u03c5 2024.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b1\u03bd \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac <strong>62 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ac \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Kleefstra<\/strong>, \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03b1\u03c0\u03cc 2 \u03ad\u03c9\u03c2 57 \u03b5\u03c4\u03ce\u03bd. \u039f\u03b9 38 \u03b5\u03af\u03c7\u03b1\u03bd \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03bf \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c4\u03bf <em>EHMT1<\/em> \u03ba\u03b1\u03b9 \u03bf\u03b9 24 \u03b4\u03b9\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae 9q34.3. \u0397 \u03bc\u03ad\u03c3\u03b7 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03c7\u03cc\u03bd\u03c4\u03c9\u03bd \u03ae\u03c4\u03b1\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 19 \u03ad\u03c4\u03b7. \u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03bd \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03ba\u03ad\u03bd\u03c4\u03c1\u03bf \u03c4\u03bf\u03c5 Radboud University Medical Center \u03c3\u03c4\u03bf Nijmegen \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03cd\u03b1\u03b6\u03b1\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2, \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03c0\u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03ba\u03b1\u03b9 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1 \u03ae\u03c4\u03b1\u03bd \u03c3\u03b1\u03c6\u03ad\u03c2: <strong>\u03bf\u03b9 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03b9 \u03bc\u03b5 Kleefstra \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c5\u03c0\u03ad\u03c1\u03b2\u03b1\u03c1\u03bf \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03bb\u03af\u03c0\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2<\/strong>, \u03ba\u03b1\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03b1\u03c1\u03c7\u03af\u03b6\u03bf\u03c5\u03bd \u03ae\u03b4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u03a4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ae\u03b4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0388\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03b9\u03bf \u03b5\u03bd\u03c4\u03c5\u03c0\u03c9\u03c3\u03b9\u03b1\u03ba\u03ac \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03ae\u03c4\u03b1\u03bd \u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03ad\u03c1\u03b2\u03b1\u03c1\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c0\u03cc \u03c4\u03b1 47 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c5\u03c0\u03ae\u03c1\u03c7\u03b1\u03bd \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1, <strong>28 \u2014 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 60% \u2014 \u03ae\u03c4\u03b1\u03bd \u03c5\u03c0\u03ad\u03c1\u03b2\u03b1\u03c1\u03b1 \u03ae \u03c0\u03b1\u03c7\u03cd\u03c3\u03b1\u03c1\u03ba\u03b1<\/strong>. \u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b1\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 BMI \u03b4\u03b5\u03bd \u03ae\u03c4\u03b1\u03bd \u03bc\u03cc\u03bd\u03bf \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03c9\u03bd \u03b5\u03bd\u03b7\u03bb\u03af\u03ba\u03c9\u03bd. \u03a6\u03b1\u03b9\u03bd\u03cc\u03c4\u03b1\u03bd \u03bd\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b5\u03c6\u03b7\u03b2\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1. \u0391\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u03b1\u03ba\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1 2\u201312 \u03b5\u03c4\u03ce\u03bd, \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03bc\u03b9\u03c3\u03bf\u03cd\u03c2 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03bf\u03cd\u03bd \u03ae\u03c4\u03b1\u03bd \u03ae\u03b4\u03b7 \u03c5\u03c0\u03ad\u03c1\u03b2\u03b1\u03c1\u03bf\u03b9 \u03ae \u03c0\u03b1\u03c7\u03cd\u03c3\u03b1\u03c1\u03ba\u03bf\u03b9.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03ad\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03c3\u03c4\u03bf Kleefstra \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03b4\u03bf\u03b8\u03b5\u03af \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03c3\u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c4\u03bf\u03bd\u03af\u03b1, \u03c3\u03c4\u03b9\u03c2 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ae \u03c3\u03b5 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1. \u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03cc\u03bc\u03c9\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c3\u03cd\u03bd\u03b8\u03b5\u03c4\u03b7.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf <em>EHMT1<\/em> \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03b5 \u03b5\u03c0\u03b9\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ce\u03bd \u03ac\u03bb\u03bb\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd. \u03a0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b1 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03c3\u03b5 \u03b6\u03ce\u03b1 \u03b5\u03af\u03c7\u03b1\u03bd \u03ae\u03b4\u03b7 \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd EHMT1\/EHMT2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 \u03bb\u03af\u03c0\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bf\u03bc\u03bf\u03b9\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7. \u0397 \u03bd\u03ad\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03ae \u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf \u03b1\u03c0\u03bf\u03c4\u03cd\u03c0\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2 \u03bc\u03b5 Kleefstra. \u0391\u03c5\u03c4\u03cc \u03b2\u03ad\u03b2\u03b1\u03b9\u03b1 <strong>\u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03cc\u03c6\u03b5\u03c5\u03ba\u03c4\u03bf<\/strong>, \u03bf\u03cd\u03c4\u03b5 \u03cc\u03c4\u03b9 \u03ba\u03ac\u03b8\u03b5 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03c2 \u03bc\u03b5 Kleefstra \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1. \u03a3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b1\u03be\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ac \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bd\u03c9\u03c1\u03af\u03c2, \u03b1\u03bd\u03c4\u03af \u03bd\u03b1 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b4\u03b5\u03c5\u03c4\u03b5\u03c1\u03b5\u03cd\u03bf\u03bd \u03b6\u03ae\u03c4\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03cc\u03bd\u03bf \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03be\u03b5\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0394\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c0\u03bf\u03cd \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03bb\u03af\u03c0\u03bf\u03c2<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03b4\u03b5\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf\u03bd \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03bc\u03ac\u03b6\u03b1\u03c2 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u039c\u03ad\u03c4\u03c1\u03b7\u03c3\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03b7\u03bd <strong>\u03c0\u03b5\u03c1\u03af\u03bc\u03b5\u03c4\u03c1\u03bf \u03c4\u03b7\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b9\u03c3\u03c7\u03af\u03c9\u03bd<\/strong>, \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03bc\u03b5\u03c4\u03c1\u03bf \u03c4\u03bf\u03c5 \u03b2\u03c1\u03b1\u03c7\u03af\u03bf\u03bd\u03b1 \u03ba\u03b1\u03b9, \u03c3\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c5\u03c0\u03bf\u03bf\u03bc\u03ac\u03b4\u03b1, \u03c4\u03b7 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03b5 \u03b2\u03b9\u03bf\u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03bc\u03c0\u03ad\u03b4\u03b7\u03c3\u03b7 \u03ae DEXA.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03c0\u03b5\u03c1\u03af\u03bc\u03b5\u03c4\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2 \u03ae\u03c4\u03b1\u03bd \u03b4\u03c5\u03c3\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03bc\u03b5\u03c4\u03c1\u03bf \u03c4\u03c9\u03bd \u03b9\u03c3\u03c7\u03af\u03c9\u03bd, \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c0\u03bf\u03c5 \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03bb\u03af\u03c0\u03bf\u03c5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bb\u03b9\u03b1\u03ba\u03ae \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae. \u0397 \u03bc\u03ad\u03c3\u03b7 \u03b1\u03bd\u03b1\u03bb\u03bf\u03b3\u03af\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03c4\u03c1\u03bf\u03c5 \u03bc\u03ad\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03cd\u03c8\u03bf\u03c2 \u03ae\u03c4\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 \u03b5\u03c0\u03c4\u03ac \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b2\u03bb\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03bb\u03b5\u03c0\u03c4\u03bf\u03bc\u03b5\u03c1\u03ad\u03c3\u03c4\u03b5\u03c1\u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, <strong>\u03cc\u03bb\u03b5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bb\u03af\u03c0\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf<\/strong>. \u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03bf \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03ad\u03c7\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc BMI \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03bb\u03af\u03c0\u03bf\u03c5\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03c4\u03bf\u03c5 BMI: \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03c3\u03c4\u03b7 \u03b6\u03c5\u03b3\u03b1\u03c1\u03b9\u03ac \u03ae \u03ad\u03bd\u03b1\u03c2 \u00ab\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc\u03c2\u00bb \u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03bc\u03ac\u03b6\u03b1\u03c2 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 <strong>\u03b4\u03b5\u03bd \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b5 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0393\u03b9\u03b1 \u03c4\u03bf Kleefstra, \u03bb\u03bf\u03b9\u03c0\u03cc\u03bd, \u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03af\u03c3\u03c9\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03ba\u03bf\u03b9\u03c4\u03ac\u03b6\u03b5\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03bc\u03b5\u03c4\u03c1\u03bf \u03c4\u03b7\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2, \u03c4\u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1, \u03c4\u03b7 \u03bc\u03c5\u03ca\u03ba\u03ae \u03bc\u03ac\u03b6\u03b1 \u03ba\u03b1\u03b9, \u03cc\u03c0\u03bf\u03c5 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7, \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u03a7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03bd\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c3\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b9 \u03c4\u03bf <strong>\u03c7\u03b1\u03bc\u03b7\u03bb\u03cc \u03b1\u03bd\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1<\/strong> \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c3\u03c5\u03c7\u03bd\u03cc \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 <strong>\u03c4\u03bf 33% \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03c7\u03cc\u03bd\u03c4\u03c9\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03b6\u03b5 \u03ba\u03bf\u03bd\u03c4\u03cc \u03b1\u03bd\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1<\/strong>. \u03a3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc \u03cc\u03c3\u03bf\u03c5\u03c2 \u03c5\u03c0\u03ae\u03c1\u03c7\u03b1\u03bd \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03cd\u03c8\u03bf\u03c2 \u03c4\u03c9\u03bd \u03b3\u03bf\u03bd\u03ad\u03c9\u03bd, \u03c4\u03bf \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03ae \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03b5\u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03bd\u03bf \u03cd\u03c8\u03bf\u03c2 \u03ae\u03c4\u03b1\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03c4\u03b1\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03cc \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03ba\u03b1\u03bc\u03c0\u03cd\u03bb\u03b5\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf \u03cd\u03c8\u03bf\u03c2 \u03c4\u03b5\u03af\u03bd\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03bc\u03b1\u03ba\u03c1\u03cd\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03bc\u03ad\u03c3\u03bf \u03cc\u03c1\u03bf \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1. \u039f\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03bd \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 <strong>\u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03b9\u03ba\u03ae \u03c9\u03c1\u03af\u03bc\u03b1\u03bd\u03c3\u03b7<\/strong>, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03bc\u03b5 Kleefstra \u03b8\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc \u03b1\u03bd\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1. \u038c\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5, \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03b4\u03b9\u03b1\u03ba\u03cd\u03bc\u03b1\u03bd\u03c3\u03b7. \u03a5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03cc\u03bc\u03c9\u03c2 \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae\u03c2 \u03cd\u03c8\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03c3\u03b5 \u03b2\u03ac\u03b8\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b9\u03b1\u03c2 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7\u03c2.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0388\u03bd\u03b1 \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae: \u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ad\u03c6\u03b5\u03c1\u03b5 \u03c3\u03c4\u03bf \u03c0\u03c1\u03bf\u03c3\u03ba\u03ae\u03bd\u03b9\u03bf \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03b6\u03ae\u03c4\u03b7\u03bc\u03b1: \u03c4\u03b7\u03bd <strong>\u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 14 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b5\u03c2 \u03c7\u03b5\u03c1\u03b9\u03bf\u03cd \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7, <strong>8 \u03b1\u03c0\u03cc \u03c4\u03b1 14 \u2014 57% \u2014 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03b6\u03b1\u03bd \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7<\/strong>. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, 10 \u03b1\u03c0\u03cc \u03c4\u03b1 14 \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c9\u03bb\u03ad\u03bd\u03b9\u03b1 \u03b1\u03c0\u03cc\u03ba\u03bb\u03b9\u03c3\u03b7, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b7 \u03c9\u03bb\u03ad\u03bd\u03b7 \u03ae\u03c4\u03b1\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b5 \u03bc\u03ae\u03ba\u03bf\u03c2 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b5\u03c1\u03ba\u03af\u03b4\u03b1. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u03af \u03b1\u03c5\u03c4\u03bf\u03af \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b1, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc <strong>\u03c0\u03bf\u03bb\u03cd \u03bc\u03b9\u03ba\u03c1\u03ae \u03c5\u03c0\u03bf\u03bf\u03bc\u03ac\u03b4\u03b1<\/strong> \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 57% \u03cc\u03bb\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03c9\u03bd \u03bc\u03b5 Kleefstra \u03ad\u03c7\u03bf\u03c5\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03c0\u03b1\u03b3\u03c1\u03cd\u03c0\u03bd\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1 \u03ae \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03ae \u03b1\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u039f \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b1\u03bd \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c3\u03b5 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c0\u03cc \u03c4\u03b1 41 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2, <strong>9 \u2014 22% \u2014 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03b6\u03b1\u03bd \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae\u03c2<\/strong>. \u03a4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03ae\u03c4\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03bc\u03ad\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03b1\u03b9\u03c4\u03af\u03b1. \u03a3\u03b5 \u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03bf \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 <strong>\u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2<\/strong>, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c3\u03c4\u03b7\u03bd \u03bf\u03c0\u03bf\u03af\u03b1 \u03c4\u03bf \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u2019 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03c3\u03c4\u03bf\u03bd \u03af\u03b4\u03b9\u03bf \u03c4\u03bf\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae \u03b1\u03b4\u03ad\u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03b8\u03b1\u03bb\u03b1\u03bc\u03bf\u03cb\u03c0\u03bf\u03c6\u03c5\u03c3\u03b9\u03b1\u03ba\u03ae \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03ae \u03c4\u03bf\u03c5. \u039f\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03b5\u03c0\u03b9\u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03cc \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b1\u03c0\u03cc \u03bc\u03af\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03bd\u03b1 \u03b8\u03b5\u03c9\u03c1\u03b7\u03b8\u03b5\u03af \u03ba\u03b1\u03b8\u03b9\u03b5\u03c1\u03c9\u03bc\u03ad\u03bd\u03bf \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03b7\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03be\u03af\u03b1 \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 <strong>\u03c4\u03cc\u03c3\u03bf \u03b7 TSH \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03b7 T4<\/strong>, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c8\u03af\u03b1.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0391\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03af\u03b4\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03c4\u03b9\u03c2 \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03ad\u03bd\u03b1 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03be\u03b5\u03c7\u03ce\u03c1\u03b9\u03c3\u03b5 \u03ae\u03c4\u03b1\u03bd \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd <strong>\u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03b9\u03b4\u03af\u03c9\u03bd<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c5\u03b3\u03b9\u03ae \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03cd\u03bb\u03bf\u03c5, \u03bf\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03bc\u03b5 Kleefstra \u03b5\u03af\u03c7\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c4\u03c1\u03b9\u03b3\u03bb\u03c5\u03ba\u03b5\u03c1\u03b9\u03b4\u03af\u03c9\u03bd. \u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03bf\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03b4\u03b5\u03bd \u03b2\u03c1\u03ae\u03ba\u03b1\u03bd \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7, \u03c4\u03b7\u03bd HDL \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd LDL. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u2014\u03b7 \u03c3\u03c5\u03c7\u03bd\u03ae \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03b7 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03ba\u03bf\u03b9\u03bb\u03b9\u03b1\u03ba\u03ae \u03b5\u03bd\u03b1\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03bb\u03af\u03c0\u03bf\u03c5\u03c2, \u03c4\u03bf \u03c5\u03c8\u03b7\u03bb\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bb\u03af\u03c0\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2\u2014 \u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03c3\u03c4\u03bf \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 Kleefstra \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd <strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf<\/strong>. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03b1\u03b9\u03b4\u03af \u03bc\u03b5 Kleefstra \u03ad\u03c7\u03b5\u03b9 \u03ae \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf. \u03a3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b1\u03c0\u03bf\u03ba\u03c4\u03bf\u03cd\u03bd \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c3\u03c5\u03bd\u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ae \u03ac\u03bb\u03bb\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03b2\u03c1\u03ae\u03ba\u03b1\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03b5\u03c1\u03b9\u03ad\u03bb\u03b1\u03b2\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03c2 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2, HbA1c \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ce\u03bd \u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd. \u039f\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2, \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b1 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1, \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03cc\u03c4\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bb\u03cc\u03b3\u03bf\u03c2 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03b7 <strong>\u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b9\u03bd\u03c3\u03bf\u03c5\u03bb\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2<\/strong>, \u03b9\u03b4\u03af\u03c9\u03c2 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03cc\u03bc\u03c9\u03c2 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03ac\u03c3\u03bf\u03c5\u03bc\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03c9\u03c2 \u00ab\u03c4\u03bf Kleefstra \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7\u00bb. \u0397 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b4\u03b5\u03bd \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03cc\u03bb\u03bf\u03b9 \u03ae \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bd \u03c3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7. \u03a4\u03bf \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 <strong>\u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0392\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03bf\u03b9 \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03bf\u03af \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 D, \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 B12, \u03c6\u03c5\u03bb\u03bb\u03b9\u03ba\u03cc \u03bf\u03be\u03cd \u03ba\u03b1\u03b9 \u03c3\u03b5\u03b9\u03c1\u03ac \u03ac\u03bb\u03bb\u03c9\u03bd \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03c4\u03c1\u03c9\u03bd.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd <strong>\u03b5\u03bb\u03bb\u03b5\u03af\u03c8\u03b5\u03b9\u03c2 \u03b2\u03b9\u03c4\u03b1\u03bc\u03b9\u03bd\u03ce\u03bd \u03c3\u03b5 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03c7\u03cc\u03bd\u03c4\u03c9\u03bd<\/strong>, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03bd\u03b1 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ac\u03b2\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03b7\u03c2 \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7\u03c2 D, \u03c4\u03b7\u03c2 B12 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c6\u03c5\u03bb\u03bb\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03c4\u03b5\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0388\u03bd\u03b1 \u03b1\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03ae\u03c4\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 <strong>\u03b1\u03bc\u03bc\u03c9\u03bd\u03af\u03b1\u03c2 \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03ae\u03c4\u03b1\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1<\/strong> \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03c4\u03c9\u03bd \u03bf\u03bc\u03ac\u03b4\u03c9\u03bd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5. \u0397 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b1\u03c5\u03c4\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03b1\u03c6\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03c4\u03bf \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c9\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03b4\u03b5\u03af\u03ba\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03b1\u03be\u03af\u03b6\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac \u03c9\u03c2 \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd \u03bf\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u038a\u03c3\u03c9\u03c2 \u03c4\u03bf \u03c0\u03b9\u03bf \u03c7\u03c1\u03ae\u03c3\u03b9\u03bc\u03bf \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03af\u03b5\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03b4\u03b5\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ae \u03c4\u03c9\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd. \u0394\u03b9\u03b1\u03c4\u03cd\u03c0\u03c9\u03c3\u03b1\u03bd \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd <strong>\u03b4\u03b9\u03b1 \u03b2\u03af\u03bf\u03c5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03bf\u03c5 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03c4\u03c1\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2<\/strong>, \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03cc\u03c3\u03bf \u03c4\u03bf \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03b6\u03c9\u03ae\u03c2. \u0393\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03c3\u03ba\u03cc\u03c0\u03b9\u03bc\u03b7 \u03c4\u03b7\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03b3\u03cd\u03c1\u03c9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03ae \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03ae \u03b1\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0393\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5 <strong>TSH \u03ba\u03b1\u03b9 fT4<\/strong>, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03c7\u03b1\u03b8\u03bf\u03cd\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03c4\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd \u03c4\u03b7\u03c2 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2, \u03c4\u03bf\u03c5 \u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7\u03c2 D, B12 \u03ba\u03b1\u03b9 \u03c6\u03c5\u03bb\u03bb\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03bc\u03b5 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03bf\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03bf\u03c5\u03bd \u03bd\u03b1 \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ae\u03b4\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd <strong>8\u201310 \u03b5\u03c4\u03ce\u03bd<\/strong> \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2\u00b7 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03ad\u03bd\u03b1 \u03ac\u03ba\u03b1\u03bc\u03c0\u03c4\u03bf \u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03af\u03b4\u03b9\u03bf \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf. \u0397 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bd\u03b1 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03c0\u03b1\u03b9\u03b4\u03af\u03b1\u03c4\u03c1\u03bf, \u03c4\u03bf\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03c3\u03c4\u03ae, \u03c4\u03bf\u03bd \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf \u03ae \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c0\u03bf\u03c5 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0397 \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0388\u03bd\u03b1 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03b7\u03bc\u03b5\u03af\u03bf \u03c4\u03b7\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf Kleefstra.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03b5\u03af \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae. \u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2, \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03bb\u03b9\u03c0\u03b9\u03b4\u03b1\u03b9\u03bc\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03c4\u03bf\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03cc\u03c4\u03b9 \u03c0\u03c1\u03b9\u03bd \u03ae \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 <strong>\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b1\u03b9\u03c4\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac \u03ae \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong>, \u03cc\u03c0\u03c9\u03c2 \u03bf \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ae \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bb\u03bb\u03b5\u03af\u03c8\u03b5\u03b9\u03c2. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b1\u03c0\u03bf\u03ba\u03c4\u03ac \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03bc\u03b5 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03c3\u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b7 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac, \u03bf \u03cd\u03c0\u03bd\u03bf\u03c2, \u03b7 \u03c8\u03c5\u03c7\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03bf\u03cd\u03bd.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03c4\u03bf EHMT1 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf <em>EHMT1<\/em> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03b5\u03c0\u03b9\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7\u03c2. \u0397 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 EHMT1 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd EHMT2 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03bc\u03ad\u03c3\u03c9 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c7\u03c1\u03c9\u03bc\u03b1\u03c4\u03af\u03bd\u03b7\u03c2. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b5\u03bd\u03cc\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03bf\u03cd \u03b1\u03bd\u03c4\u03b9\u03b3\u03c1\u03ac\u03c6\u03bf\u03c5 \u03c4\u03bf\u03c5 <em>EHMT1<\/em> \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ce\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03bf\u03b4\u03ce\u03bd \u2014 \u03cc\u03c7\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b5\u03ba\u03b5\u03af\u03bd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bd\u03b5\u03c5\u03c1\u03c9\u03bd\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a3\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1, \u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03b7\u03c2 \u03af\u03b4\u03b9\u03b1\u03c2 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bd\u03b4\u03b5\u03b8\u03b5\u03af \u03bc\u03b5 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03bf\u03c5 \u03bb\u03b9\u03c0\u03ce\u03b4\u03bf\u03c5\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd, \u03c3\u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03c4\u03c1\u03cc\u03c0\u03bf \u03bc\u03b5 \u03c4\u03bf\u03bd \u03bf\u03c0\u03bf\u03af\u03bf \u03bf \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03b9\u03b1\u03c7\u03b5\u03b9\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03b1\u03c0\u03bf\u03b8\u03ad\u03bc\u03b1\u03c4\u03b1. \u0397 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03af\u03b1 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c5\u03c8\u03b7\u03bb\u03ae \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bb\u03af\u03c0\u03bf\u03c5\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03bd\u03b1 \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd \u03cc\u03c4\u03b9 <strong>\u03c4\u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2<\/strong>. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a0\u03b1\u03c1\u03cc\u03bb\u03b1 \u03b1\u03c5\u03c4\u03ac, \u03b7 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c0\u03bf\u03bb\u03c5\u03c0\u03b1\u03c1\u03b1\u03b3\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae. \u0397 \u03c5\u03c0\u03bf\u03c4\u03bf\u03bd\u03af\u03b1, \u03b7 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c0\u03b7\u03c1\u03af\u03b1, \u03bf\u03b9 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2, \u03bf \u03cd\u03c0\u03bd\u03bf\u03c2, \u03c4\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5.<\/p>\n\n\n\n<div class=\"wp-block-group study-meaning\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b1\u03c5\u03c4\u03ae \u03b7 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u00ab\u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 Kleefstra \u03b8\u03b1 \u03b3\u03af\u03bd\u03bf\u03c5\u03bd \u03c0\u03b1\u03c7\u03cd\u03c3\u03b1\u03c1\u03ba\u03b1\u00bb.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03bf \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 <strong>\u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5<\/strong>, \u03cc\u03c0\u03c9\u03c2 \u03ae\u03b4\u03b7 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7, \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03af\u03b1, \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bb\u03b7\u03c8\u03af\u03b1, \u03c4\u03bf\u03bd \u03cd\u03c0\u03bd\u03bf \u03ae \u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03b8\u03ad\u03bc\u03b1 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03bf\u03cd\u03c4\u03b5 \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u00ab\u03ba\u03b1\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac\u03c2\u00bb \u03ae \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2. \u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 <strong>\u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7<\/strong>, \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 EHMT1. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0391\u03c5\u03c4\u03cc \u03ba\u03ac\u03bd\u03b5\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7: \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03b1\u03c0\u03cc \u03bc\u03b9\u03ba\u03c1\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03cc\u03c3\u03bf \u03c4\u03bf \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03b1\u03b9\u03b4\u03b9\u03bf\u03cd, \u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae, \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03c4\u03c1\u03c9\u03bd \u03cc\u03c4\u03b1\u03bd \u03b5\u03bd\u03b4\u03b5\u03af\u03ba\u03bd\u03c5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u039a\u03b1\u03b9, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c7\u03b5\u03b4\u03cc\u03bd \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c4\u03c5\u03c7\u03ae \u03c4\u03bf\u03c5 Kleefstra, <strong>\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9<\/strong>.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group study-conclusion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">\u039c\u03b9\u03b1 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 Kleefstra<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd Bouman \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03c4\u03ce\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03bc\u03b1\u03c2 \u03c5\u03c0\u03b5\u03bd\u03b8\u03c5\u03bc\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf KLEFS1 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b9\u03b1 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf\u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf <em>EHMT1<\/em> \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03ba\u03c4\u03b5\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd. \u0397 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2, \u03b7 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c4\u03bf \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03bd\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1, \u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2, \u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03bf\u03bc\u03bc\u03ac\u03c4\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03b1\u03be\u03af\u03b1 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03bd\u03ce\u03c3\u03b7\u03c2 \u03b4\u03b5\u03bd \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2. \u0392\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ce\u03c2 \u03c3\u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03bf: <strong>\u03c3\u03b5 \u03cc\u03c3\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03c3\u03bf\u03c5\u03bc\u03b5 \u03b5\u03b3\u03ba\u03b1\u03af\u03c1\u03c9\u03c2, \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03bf\u03c5\u03bc\u03b5 \u03b5\u03b3\u03ba\u03b1\u03af\u03c1\u03c9\u03c2<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0397 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b1\u03c5\u03c4\u03ae \u03ad\u03b4\u03c9\u03c3\u03b5 \u03b3\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03c0\u03b9\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03ce\u03c3\u03c4\u03b5 \u03b7 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03b5\u03bd\u03cc\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5 \u03bc\u03b5 Kleefstra \u03bd\u03b1 \u03bc\u03b7\u03bd \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf \u03c4\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf, \u03b1\u03bb\u03bb\u03ac \u03bd\u03b1 \u03b2\u03bb\u03ad\u03c0\u03b5\u03b9 \u03c4\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac \u2014 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03ae \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc, \u03c4\u03b1 \u03bf\u03c3\u03c4\u03ac \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c4\u03bf\u03c5 \u03c5\u03b3\u03b5\u03af\u03b1.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group study-source\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">\u03a0\u03b7\u03b3\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Bouman A, Geelen JM, Kummeling J, Schenck A, van der Zwan YG, Klein WM, Kleefstra T.<\/strong> <em>Growth, body composition, and endocrine-metabolic profiles of individuals with Kleefstra syndrome provide directions for clinical management and translational studies.<\/em> American Journal of Medical Genetics Part A. 2024;194(5):e63472. doi:10.1002\/ajmg.a.63472. \u0397 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03b9\u03c2 29 \u0394\u03b5\u03ba\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2023 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03c4\u03ac\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf\u03bd \u03c4\u03cc\u03bc\u03bf \u03c4\u03bf\u03c5 2024. (<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/ajmg.a.63472\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a>)<\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u03a4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Kleefstra \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c9\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae. \u0397 \u03c5\u03c0\u03bf\u03c4\u03bf\u03bd\u03af\u03b1, \u03b7 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7, \u03bf\u03b9&#8230;<\/p>\n","protected":false},"author":1,"featured_media":2479,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"categories":[9],"tags":[183,166,178,36,174,165,37,130,172,168,170,176,180,182,184,103,175,177,185,173,179,169,97,167,181,171],"class_list":["post-2234","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-bmi","tag-body-composition","tag-bone-health","tag-ehmt1","tag-endocrine","tag-growth","tag-kleefstra-syndrome","tag-klefs1","tag-metabolism","tag-obesity","tag-overweight","tag-thyroid","tag-triglycerides","tag-vitamin-d","tag-waist-circumference","tag-103","tag-175","tag-177","tag-185","tag-173","tag-179","tag-169","tag--kleefstra","tag-167","tag-181","tag-171"],"yoast_head":"<!-- This site is optimized with the Yoast 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