{"id":192,"date":"2018-02-04T22:44:43","date_gmt":"2018-02-04T22:44:43","guid":{"rendered":"http:\/\/kleefstrasyndrome.com\/?p=192"},"modified":"2022-12-30T21:12:01","modified_gmt":"2022-12-30T19:12:01","slug":"case-study-on-antipsychotics-for-kleefstra-patients","status":"publish","type":"post","link":"https:\/\/kleefstrasyndrome.com\/en\/case-study-on-antipsychotics-for-kleefstra-patients\/","title":{"rendered":"\u039d\u03ad\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03cd\u03c0\u03bd\u03bf"},"content":{"rendered":"<!-- Global site tag (gtag.js) - Google Analytics -->\n<script async=\"\" src=\"https:\/\/www.googletagmanager.com\/gtag\/js?id=UA-91563252-1\"><\/script>\n<script>\n  window.dataLayer = window.dataLayer || [];\n  function gtag(){dataLayer.push(arguments);}\n  gtag('js', new Date());\n\n  gtag('config', 'UA-91563252-1');\n<\/script>\n\n\n\n<p>\u039d\u03ad\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c0\u03cc \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 Radboud \u03c3\u03c4\u03bf \u039d\u03b1\u03ca\u03bc\u03ad\u03c7\u03b5\u03bd \u03c4\u03b7\u03c2 \u039f\u03bb\u03bb\u03b1\u03bd\u03b4\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 Dr. Kleefstra \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc Clinical Neuropharmacology (\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u039d\u03b5\u03c5\u03c1\u03bf\u03c6\u03b1\u03c1\u03bc\u03bf\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1) \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c7\u03b5\u03b9\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5 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\u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03ac\u03c1\u03bd\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c6\u03b1\u03b3\u03b7\u03c4\u03cc. \u03a4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03bd\u03c4\u03b1\u03bd\u03b1\u03ba\u03bb\u03bf\u03cd\u03c3\u03b1\u03bd \u03ad\u03bd\u03b1 \u03bc\u03b1\u03bd\u03b9\u03b1\u03ba\u03cc-\u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03cc \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03bf \u03ba\u03b1\u03b9 \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac \u03b2\u03b5\u03bd\u03b6\u03bf\u03b4\u03b9\u03b1\u03b6\u03b5\u03c0\u03af\u03bd\u03b5\u03c2, \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bc\u03c9\u03c2 \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u038e\u03c3\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03bf\u03bb\u03b1\u03bd\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 (17.5mg\/\u03bc\u03ad\u03c1\u03b1) \u03bf \u03cd\u03c0\u03bd\u03bf\u03c2 \u03b5\u03c0\u03ad\u03c3\u03c4\u03c1\u03b5\u03c8\u03b5 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03ac \u03c4\u03bf\u03c5 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 24 \u03ce\u03c1\u03b5\u03c2. \u0391\u03bc\u03ad\u03c3\u03c9\u03c2 \u03bc\u03b5\u03c4\u03ac, \u03bf\u03b9 \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac \u03ba\u03b1\u03b9 \u03bf\u03bc\u03b9\u03bb\u03af\u03b5\u03c2 \u03c3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c3\u03b1\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac \u03ba\u03b1\u03b9 \u03b7 \u03cc\u03c1\u03b5\u03be\u03b7 \u03bf\u03bc\u03b1\u03bb\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd.<\/p>\n\n\n\n<p>\u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u039a\u03bb\u03af\u03bc\u03b1\u03ba\u03b1 \u03a0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac\u03c2 Vineland (Vineland Adaptive Behavior Scales) \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03ae\u03c4\u03b1\u03bd \u03b1\u03c4\u03cc\u03bc\u03bf\u03c5 2 \u03c7\u03c1\u03bf\u03bd\u03ce\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd 12 \u03c7\u03c1\u03bf\u03bd\u03ce\u03bd. \u0397 \u03b5\u03c0\u03b1\u03bd\u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 15 \u03c7\u03c1\u03bf\u03bd\u03ce\u03bd (6 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03cd\u03c3\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c1\u03c1\u03c9\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b5\u03c0\u03b5\u03b9\u03c3\u03cc\u03b4\u03b9\u03bf \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03b7\u03ba\u03b5 \u03c0\u03b1\u03c1\u03b1\u03c0\u03ac\u03bd\u03c9) \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf\u03bd 1 \u03c7\u03c1\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 5 \u03bc\u03b7\u03bd\u03ce\u03bd. \u03a4\u03bf \u03c0\u03b1\u03b9\u03b4\u03af \u03b5\u03af\u03c7\u03b5 \u03c7\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03bc\u03b9\u03bb\u03ac\u03b5\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03ac \u03c4\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ad\u03b4\u03b5\u03b9\u03c7\u03bd\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c5\u03c4\u03bf\u03c4\u03c1\u03b1\u03c5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac.<\/p>\n\n\n\n<p><strong>2\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7<\/strong>: \u0397 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03ba\u03bf\u03c1\u03af\u03c4\u03c3\u03b9 23 \u03b5\u03c4\u03ce\u03bd \u03bc\u03b5 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03bd\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c0\u03b7\u03c1\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9<br>(\u03b1) \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03b8\u03c5\u03c3\u03c4\u03ad\u03c1\u03b7\u03c3\u03b7<br>(\u03b2) \u03b4\u03c5\u03c3\u03ba\u03bf\u03b9\u03bb\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<br>(\u03b3) \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u0391\u03c5\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03a6\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2<\/p>\n\n\n\n<p>\u0395\u03af\u03c7\u03b5 \u03bc\u03b7 \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03ad\u03bc\u03bc\u03b7\u03bd\u03b5\u03c2 \u03c1\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03ad\u03bd\u03b1 \u03b5\u03bd\u03b4\u03bf\u03bc\u03c5\u03ca\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf (Provera). \u038e\u03c3\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03b1\u03b3\u03ac\u03c0\u03b7 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 18 \u03b5\u03c4\u03ce\u03bd \u03b1\u03bd\u03ad\u03c0\u03c4\u03c5\u03be\u03b5 \u03bc\u03b5\u03af\u03b6\u03c9\u03bd \u03ba\u03b1\u03c4\u03b1\u03b8\u03bb\u03b9\u03c0\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03ac\u03b3\u03c7\u03bf\u03c5\u03c2 \u03bc\u03b5 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03bf\u03bd \u03cd\u03c0\u03bd\u03bf. \u03a6\u03bf\u03b2\u03cc\u03c4\u03b1\u03bd \u03bd\u03b1 \u03ba\u03bf\u03b9\u03bc\u03b7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03be\u03c5\u03c0\u03bd\u03bf\u03cd\u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03ce\u03c1\u03b5\u03c2 \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03cc (\u03ba\u03bf\u03b9\u03bc\u03cc\u03c4\u03b1\u03bd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc 4 \u03ce\u03c1\u03b5\u03c2 \u03c4\u03b7 \u03bd\u03cd\u03c7\u03c4\u03b1). \u0397 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03c1\u03b9\u03c0\u03b9\u03c0\u03c1\u03b1\u03b6\u03cc\u03bb\u03b7 \u03be\u03b5\u03ba\u03af\u03bd\u03b7\u03c3\u03b5 \u03bc\u03b5 \u03b4\u03cc\u03c3\u03b7 2,5mg \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c5\u03b5\u03c1\u03b5\u03b8\u03b9\u03c3\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03c3\u03b5 \u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03b1\u03c5\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03c6\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2. \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c0\u03c1\u03bf\u03ba\u03ac\u03bb\u03b5\u03c3\u03b5 \u03c5\u03c0\u03bd\u03b7\u03bb\u03af\u03b1, \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b1 2mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2.<\/p>\n\n\n\n<p>\u039c\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b1 2 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b1\u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b5 \u03cc\u03c0\u03c9\u03c2 \u03bd\u03b1 \u03bd\u03c4\u03cd\u03bd\u03b5\u03c4\u03b1\u03b9, \u03bd\u03b1 \u03b3\u03c1\u03ac\u03c6\u03b5\u03b9, \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03b9, \u03bd\u03b1 \u03bc\u03b9\u03bb\u03ac\u03b5\u03b9 \u03bc\u03b5 \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03ae. \u0395\u03be\u03b1\u03b9\u03c4\u03af\u03b1\u03c2 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2, \u03c7\u03c1\u03b5\u03b9\u03b1\u03b6\u03cc\u03c4\u03b1\u03bd \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 24 \u03ce\u03c1\u03b5\u03c2 \u03c4\u03bf 24\u03c9\u03c1\u03bf, 7 \u03bc\u03ad\u03c1\u03b5\u03c2 \u03c4\u03b7 \u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03b3\u03b9\u2019 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03bb\u03cc\u03b3\u03bf \u03b5\u03b9\u03c3\u03ae\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b7\u03bd \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c0\u03c4\u03ad\u03c1\u03c5\u03b3\u03b1.<\/p>\n\n\n\n<p>\u0395\u03c0\u03b5\u03b9\u03b4\u03ae \u03b7 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03bf\u03cd\u03c3\u03b5, \u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c1\u03b9\u03c0\u03b9\u03c0\u03c1\u03b1\u03b6\u03cc\u03bb\u03b7\u03c2 \u03b1\u03c5\u03be\u03b1\u03bd\u03cc\u03c4\u03b1\u03bd \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac. \u03a3\u03c4\u03b1 15mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03c4\u03b1 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03cd\u03c0\u03bd\u03bf\u03c5 \u03c3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c3\u03b1 \u03cc\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03ba\u03b1\u03c4\u03b1\u03b8\u03bb\u03b9\u03c0\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u0397 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c3\u03b5 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03c6\u03b5\u03c1\u03b5 \u03bd\u03b1 \u03be\u03b1\u03bd\u03b1\u03ba\u03b5\u03c1\u03b4\u03af\u03c3\u03b5\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03b5\u03be\u03b9\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c4\u03b7\u03c2: \u03bd\u03b1 \u03bc\u03b9\u03bb\u03ac\u03b5\u03b9 \u03bc\u03b5 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03af\u03c7\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03b5\u03c0\u03af\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b6\u03b7\u03c4\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03ae\u03c2 \u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03ae\u03c2.<\/p>\n\n\n\n<p><strong>3\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7<\/strong>: \u0397 \u03c4\u03c1\u03af\u03c4\u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ad\u03bd\u03b1 \u03ba\u03bf\u03c1\u03af\u03c4\u03c3\u03b9 23 \u03b5\u03c4\u03ce\u03bd \u03bc\u03b5 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03bd\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c0\u03b7\u03c1\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9<br>(\u03b1) \u03a0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b2\u03c1\u03b1\u03c6\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1<br>(\u03b2) \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03c4\u03c9\u03bd \u03b1\u03b5\u03c1\u03b1\u03b3\u03c9\u03b3\u03ce\u03bd<br>(\u03b3) \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7<br>(\u03b4) \u03b4\u03c5\u03c3\u03ba\u03bf\u03b9\u03bb\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1<br>(\u03b5) \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03ad\u03bc\u03bc\u03b7\u03bd\u03bf\u03c5 \u03c1\u03cd\u03c3\u03b5\u03c9\u03c2.<\/p>\n\n\n\n<p>\u03a4\u03bf \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03c4\u03b7\u03c2 \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b1\u03c5\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 20 \u03b5\u03c4\u03ce\u03bd, \u03c0\u03bf\u03c5 \u03c0\u03ad\u03b8\u03b1\u03bd\u03b5 \u03bf \u03c0\u03b1\u03c0\u03c0\u03bf\u03cd\u03c2 \u03c4\u03b7\u03c2. \u03a3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c3\u03b5 \u03bd\u03b1 \u03ba\u03bf\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03bd\u03cd\u03c7\u03c4\u03b5\u03c2, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03b1\u03c0\u03ac\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c8\u03b5\u03c5\u03b4\u03b1\u03b9\u03c3\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2.<br>\u0393\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03ad\u03c0\u03b1\u03b9\u03c1\u03bd\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b1\u03bb\u03bb\u03ac \u03b4\u03b5\u03bd \u03ae\u03c4\u03b1\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ad\u03c2 \u03b5\u03c9\u03c2 \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03b9\u03c0\u03b1\u03bc\u03c0\u03b5\u03c1\u03cc\u03bd\u03b7\u03c2 (20mg, 2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03bb\u03bf\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bb\u03b7\u03c2 (2mg, 2 \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2)<br>\u03a0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03bb\u03bf\u03c1\u03b1\u03b6\u03b5\u03c0\u03ac\u03bc\u03b7 (4 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc 2mg) \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 50mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03b6\u03bf\u03c5\u03ba\u03bb\u03bf\u03c0\u03b5\u03bd\u03b8\u03b9\u03be\u03cc\u03bb\u03b7 \u03ba\u03b1\u03b9 50mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2 \u03c0\u03c1\u03bf\u03bc\u03b5\u03b8\u03b1\u03b6\u03af\u03bd\u03b7 \u03b4\u03b5\u03bd \u03ad\u03c6\u03b5\u03c1\u03b1\u03bd \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1. \u039c\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b1 2 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03c7\u03ce\u03c1\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03b5\u03be\u03b9\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd \u03c4\u03b7\u03c2. \u0388\u03c7\u03b1\u03c3\u03b5 \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03bc\u03b9\u03bb\u03ac\u03b5\u03b9, \u03bd\u03b1 \u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b6\u03b5\u03b9, \u03bd\u03b1 \u03bd\u03c4\u03cd\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03ba\u03bf\u03bb\u03c5\u03bc\u03c0\u03ac\u03b5\u03b9. \u0395\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03c3\u03c5\u03bb\u03bb\u03b9\u03c0\u03c4\u03b9\u03ba\u03ce\u03bd \u03c7\u03b1\u03c0\u03b9\u03ce\u03bd \u03c3\u03b7\u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03b1\u03b9\u03c6\u03bd\u03af\u03b4\u03b9\u03b1 \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n\n\n\n<p>\u03a3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 22 \u03b5\u03c4\u03ce\u03bd \u03b5\u03b9\u03c3\u03ae\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b7\u03bd \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03cd\u03c2 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03be\u03b5\u03ba\u03af\u03bd\u03b7\u03c3\u03b5 \u03bc\u03b5 \u03bf\u03bb\u03b1\u03bd\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 25mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2. \u03a0\u03b1\u03c1\u03ac \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae, \u03b5\u03be\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03cb\u03c0\u03bd\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c5\u03c0\u03cc\u03c6\u03b5\u03c1\u03b5 \u03b1\u03c0\u03cc \u03c8\u03b5\u03c5\u03b4\u03b1\u03b9\u03c3\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2. \u038c\u03bc\u03c9\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bf\u03bb\u03b1\u03bd\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03bf\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 (50mg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2) \u03c3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c3\u03b5 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 \u03cd\u03c0\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1. \u039a\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b1\u03c5\u03c4\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b5\u03c0\u03b5\u03b9\u03c3\u03bf\u03b4\u03af\u03bf\u03c5, \u03c4\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1 \u03a0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ac\u03c2 Vineland \u03ae\u03c4\u03b1\u03bd 1 \u03ad\u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 3 \u03bc\u03b7\u03bd\u03ce\u03bd, \u03b5\u03bd\u03ce \u03c3\u03c4\u03bf \u03c0\u03b1\u03c1\u03b5\u03bb\u03b8\u03cc\u03bd (\u03c3\u03b5 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 16 \u03b5\u03c4\u03ce\u03bd), \u03b7 \u03bc\u03ad\u03c4\u03c1\u03b7\u03c3\u03b7 \u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03cd\u03c3\u03b5 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd 3 \u03b5\u03c4\u03ce\u03bd.<\/p>\n\n\n\n<p>\u0391\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03bf\u03cd\u03c3\u03b1\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd 3 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd \u03b4\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03ba\u03ac\u03c4\u03c9 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7.<br><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28622207\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28622207<\/a><br>\u0391\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b5 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bb\u03ae\u03c8\u03b7 \u03c4\u03bf\u03c5 paper, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03ae\u03c3\u03b5\u03c4\u03b5 \u03bc\u03b1\u03b6\u03af \u03bc\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c3\u03b1\u03c2 \u03c4\u03bf \u03c0\u03c1\u03bf\u03c9\u03b8\u03ae\u03c3\u03c9.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u039d\u03ad\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c0\u03cc \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 Radboud \u03c3\u03c4\u03bf \u039d\u03b1\u03ca\u03bc\u03ad\u03c7\u03b5\u03bd \u03c4\u03b7\u03c2 \u039f\u03bb\u03bb\u03b1\u03bd\u03b4\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 Dr. Kleefstra&#8230;<\/p>","protected":false},"author":1,"featured_media":530,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"aside","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"categories":[9],"tags":[15,16,13,17,14],"class_list":["post-192","post","type-post","status-publish","format-aside","has-post-thumbnail","hentry","category-research","tag-antipsychotics","tag-drugs","tag-kleefstra","tag-pharmaceutical","tag-sleep-disturbance","post_format-post-format-aside"],"_links":{"self":[{"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/posts\/192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/comments?post=192"}],"version-history":[{"count":9,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/posts\/192\/revisions"}],"predecessor-version":[{"id":531,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/posts\/192\/revisions\/531"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/media\/530"}],"wp:attachment":[{"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/media?parent=192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/categories?post=192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kleefstrasyndrome.com\/en\/wp-json\/wp\/v2\/tags?post=192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}